Activities - Event View

Symposium

December 4^th, 2019, Boston, USA

“Gene Regulation in Differentiation and Cancer”

Agenda

8:45-9:15 Registration and Continental breakfast

9:15-9:30 Opening Remarks 

Alan Rosmarin, M.D.

9.30-11:15 Session I:   

Chair: Dr. Alan Rosmarin

9.30-10:00 Keynote Speaker

Jonathan Licht M.D.

Director- The University of Florida Health Cancer Center,

The Marshall E. Rinker, Sr. Foundation and David B. and Leighan R. Rinker Chair

Disorders of histones and histone methylation in cancer 

10:00 to 10:15 Ulrich Steidl, M.D. Ph.D.

Lineage Commitment and Differentiation – 15 years later

10:15-1:30 Shannon Elf, Ph.D.

Identifying novel molecular dependencies in CALR-mutated myeloproliferative neoplasms

10:30-10:45 Huimin Chen, M.D. Ph.D.

3D Bioprinting Application in Cartilage Repair

10:45-11:00 Annalisa DiRuscio, M.D. Ph.D.

RNAs: the real writers of the epigenetic code

11:00-11:15 Sophia Adamia, Ph.D.

AML epigenetics for the 21st century: novel biomarkers and drug targets

11:15-12:30             Session II

                                Chair: Dr. Ulrich Steidl

11:15-11:30 Dong-Er Zhang, Ph.D.

Dynamics of RASSF2 in leukemogenesis

11:30-11:45 Justin Wheat, Ph.D.

Single Molecule Analysis of Spi1 Transcription Dynamics During Differentiation

11:45-12:00 Meritxell Alberich-Jorda, Ph.D.

Chronic inflammation, stem cells and leukemia

12:00-12:15 Britta Will, Ph.D.

Novel safeguards of hematopoietic stem cell identity

12:15-12:30 Barbara Wegiel, Ph.D.

Scavenging of free heme by hemopexin is a key check-point in cancer growth and     metastases

12:30-1:30 Lunch break

1:30-3:30 Session III

Chair: Dr. Dong-Er Zhang

1:30-2:00 Keynote Speaker

David Livingston, M.D.,

Deputy Director, Dana-Farber/Harvard Cancer Center

Chief, Charles A. Dana Division of Human Cancer Genetics

Emil Frei Professor of Genetics and Medicine, 

Harvard Medical School, Dana-Farber Cancer Institute, Boston, Massachusetts               

En route in a normal mammary epithelial cell to BRCA1 breast cancer

2:00-2:15 Dan Costa, M.D., Ph.D.

Dan Tenen and lung cancer: an accidental encounter that helped revolutionize precision    oncology

2:15-2:30 Gang Huang, Ph.D.

Pseudohypoxia - An Underlying Mechanism and therapeutic Target of Myelodysplastic Syndromes

2:30-2:45 Hideyo Hirai, MD. Ph.D.

C/EBPbeta isoforms regulate hematopoietic stem cells under stress condition

 2:45-3:00 Philipp Staber, MD. Ph.D.

Identifying functional switches in hematologic malignancies

3:00-3:15 Rob Welner, Ph.D.

Targeting Leukemia through the Marrow Microenvironment

3:15-3:30 Anne Satterthwaite, Ph.D.

Signals controlling plasma cell accumulation and autoantibody production in lupus

3:30-3:45 Coffee Break

3:45-5:30 Session IV

Chair: Dr. Dan Costa

3:45-4:00 Alan Rosmarin, MD.

A tribute to Dan Tenen

4:00-4:15 Elena Levantini, Ph.D.

Identification of a targetable KRAS-mutant epithelial population in NSCLC

4:15-4:30 Li Chai, M.D.

Targeting SALL4 in Cancer

4:30-4:45 Omid Harandi, Ph.D.

MRNA-based Engineering of Red Cell Therapeutics (RCTs) to Generate Potent, Allogeneic Cellular Therapies

4:45-5:00 Bon Trinh, Ph.D.

  RNA Regulation of Promoter-Enhancer Communication

5:00-5:15 Balazs Halmos, MD. Ph.D.

Precision lung cancer medicine- a "personal" journey

5:15-5:45 Closing ceremony

Daniel G. Tenen, M.D.

5:45-6:00 Group Picture

6:00-8:30 Dinner party (Invited only)

Gene Regulation in Differentiation and Cancer
December 4^th 2019

Honoring Daniel G. Tenen, M.D.

For his many contributions to the scientific community

 Date:      Wednesday December 4^th, 2019                

 Time:      8:45am – 6:00pm

 Location:       DFCI Jimmy Fund Auditorium

Binney Street,

Boston, MA, 02115

Symposium Committee Co-Chairs

Alan G. Rosmarin, M.D.

Deputy Editor of Hematology at UpToDate

Chief Mission Officer, the Samuel Waxman Cancer Research Foundation.

Dong-Er Zhang, Ph.D.

Professor of Pathology and Biological Sciences
University of California San Diego
Moores UCSD Cancer Center
La Jolla, CA

Ulrich Steidl, M.D., Ph.D.

Professor of Cell Biology and Medicine,
Albert Einstein College of Medicine - Montefiore Medical Center
New York, NY

Daniel Costa, M.D., Ph.D.

Associate Professor of Medicine, Harvard Medical School

Co-director Lung cancer research program within Cancer Research Institute at BIDMC

Co-leader of the lung cancer program at Dana-Farber/Harvard Cancer Center

Symposium Organizing Committee Contacts: 

gang.huang@cchmc.org

lchai@bwh.harvard.edu

pu.zhang@Novartis.com