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HomeIABMR Minisymposium 2019

IABMR Minisymposium 2019: Gene Regulation in Differentiation and Cancer - 12/4/2019

Go to the main website (link above) to register!


December 4th, 2019, Boston, USA

“Gene Regulation in Differentiation and Cancer”



8:45-9:15 Registration and Continental breakfast


9:15-9:30 Opening Remarks 

Alan Rosmarin, M.D.

9.30-11:15 Session I:   

Chair: Dr. Alan Rosmarin


9.30-10:00 Keynote Speaker

Jonathan Licht M.D.

Director- The University of Florida Health Cancer Center,

The Marshall E. Rinker, Sr. Foundation and David B. and Leighan R. Rinker Chair

Disorders of histones and histone methylation in cancer 


10:00 to 10:15 Ulrich Steidl, M.D. Ph.D.

Lineage Commitment and Differentiation – 15 years later


10:15-1:30 Shannon Elf, Ph.D.

Identifying novel molecular dependencies in CALR-mutated myeloproliferative neoplasms



10:30-10:45 Huimin Chen, M.D. Ph.D.

3D Bioprinting Application in Cartilage Repair


10:45-11:00 Annalisa DiRuscio, M.D. Ph.D.

RNAs: the real writers of the epigenetic code


11:00-11:15 Sophia Adamia, Ph.D.

AML epigenetics for the 21st century: novel biomarkers and drug targets



11:15-12:30             Session II

                                Chair: Dr. Ulrich Steidl


11:15-11:30 Dong-Er Zhang, Ph.D.

Dynamics of RASSF2 in leukemogenesis


11:30-11:45 Justin Wheat, Ph.D.

Single Molecule Analysis of Spi1 Transcription Dynamics During Differentiation


11:45-12:00 Meritxell Alberich-Jorda, Ph.D.

Chronic inflammation, stem cells and leukemia


12:00-12:15 Britta Will, Ph.D.

Novel safeguards of hematopoietic stem cell identity


12:15-12:30 Barbara Wegiel, Ph.D.

Scavenging of free heme by hemopexin is a key check-point in cancer growth and     metastases



12:30-1:30 Lunch break



1:30-3:30 Session III

Chair: Dr. Dong-Er Zhang


1:30-2:00 Keynote Speaker

David Livingston, M.D.,

Deputy Director, Dana-Farber/Harvard Cancer Center

Chief, Charles A. Dana Division of Human Cancer Genetics

Emil Frei Professor of Genetics and Medicine, 

Harvard Medical School, Dana-Farber Cancer Institute, Boston, Massachusetts               

En route in a normal mammary epithelial cell to BRCA1 breast cancer


2:00-2:15 Dan Costa, M.D., Ph.D.

Dan Tenen and lung cancer: an accidental encounter that helped revolutionize precision    oncology


2:15-2:30 Gang Huang, Ph.D.

Pseudohypoxia - An Underlying Mechanism and therapeutic Target of Myelodysplastic Syndromes


2:30-2:45 Hideyo Hirai, MD. Ph.D.

C/EBPbeta isoforms regulate hematopoietic stem cells under stress condition


 2:45-3:00 Philipp Staber, MD. Ph.D.

Identifying functional switches in hematologic malignancies


3:00-3:15 Rob Welner, Ph.D.

Targeting Leukemia through the Marrow Microenvironment


3:15-3:30 Anne Satterthwaite, Ph.D.

Signals controlling plasma cell accumulation and autoantibody production in lupus



3:30-3:45 Coffee Break



3:45-5:30 Session IV

Chair: Dr. Dan Costa

3:45-4:00 Alan Rosmarin, MD.

A tribute to Dan Tenen


4:00-4:15 Elena Levantini, Ph.D.

Identification of a targetable KRAS-mutant epithelial population in NSCLC


4:15-4:30 Li Chai, M.D.

Targeting SALL4 in Cancer


4:30-4:45 Omid Harandi, Ph.D.

MRNA-based Engineering of Red Cell Therapeutics (RCTs) to Generate Potent, Allogeneic Cellular Therapies


4:45-5:00 Bon Trinh, Ph.D.

  RNA Regulation of Promoter-Enhancer Communication


5:00-5:15 Balazs Halmos, MD. Ph.D.

Precision lung cancer medicine- a "personal" journey



5:15-5:45 Closing ceremony

Daniel G. Tenen, M.D.


5:45-6:00 Group Picture


6:00-8:30 Dinner party (Invited only)


Symposium Flyer Picture

Gene Regulation in Differentiation and Cancer
December 4th 2019



Honoring Daniel G. Tenen, M.D.


For his many contributions to the scientific community


 Date:      Wednesday December 4th, 2019                


 Time:      8:45am – 6:00pm


 Location:       DFCI Jimmy Fund Auditorium

Binney Street,

Boston, MA, 02115



Symposium Committee Co-Chairs


Alan G. Rosmarin, M.D.

Deputy Editor of Hematology at UpToDate

Chief Mission Officer, the Samuel Waxman Cancer Research Foundation.


Dong-Er Zhang, Ph.D.

Professor of Pathology and Biological Sciences
University of California San Diego
Moores UCSD Cancer Center
La Jolla, CA


Ulrich Steidl, M.D., Ph.D.

Professor of Cell Biology and Medicine,
Albert Einstein College of Medicine - Montefiore Medical Center
New York, NY


Daniel Costa, M.D., Ph.D.

Associate Professor of Medicine, Harvard Medical School

Co-director Lung cancer research program within Cancer Research Institute at BIDMC

Co-leader of the lung cancer program at Dana-Farber/Harvard Cancer Center

Symposium Organizing Committee Contacts: