Yumei Zhan, MD; PhD
Cardiology Division, Department of Medicine
Beth Israel Deaconess Medical Center
99 Brookline Ave, RM253
Boston, MA 02115
To investigate roles of ETS transcription factor members in vascular inflammation and remodeling.
Selected peer-reviewed publications.
Zhan Y; Yuan L; Oettgen P. Alterations in transcriptional responses associated with vascular aging. Journal of inflammation (London, England) 2009;6:16.
Yuan L; Nikolova-Krstevski V; Zhan Y, etc. Antiinflammatory effects of the ETS factor ERG in endothelial cells are mediated through transcriptional repression of the interleukin-8 gene. Circ Res. 2009;104(9):1049-57.
Peng H, Tan L, Osaki M, Zhan Y, etc. ESE-1 is a potent repressor of type II Collagen gene (COL2A1) transcription in human chondrocytes. J Cell Physiol. 2007 Nov28.
Ni W, Zhan Y, He H, Maynard E, Balschi JA, Oettgen P. Ets-1 Is a Critical Transcriptional Regulator of Reactive Oxygen Species and p47phox Gene Expression in Response to Angiotensin II. Circ Res. 2007,101.
Zhan Y, Brown C, Maynard E, Anshelevich A, Ni W, Ho I, and Oettgen P. Ets-1 is a critical regulator of angiotensin II mediated vascular inflammation and remodeling. J Clin Invest. 2005 115(9):2508-2516.
Zhan Y, Kim S, Izumi Y, Izumiya Y, Nakao T, Miyazaki H, Iwao H. Role of JNK, p38, and ERK in Platelet-Derived Growth Factor-Induced Vascular Proliferation, Migration, and Gene Expression. Arterioscler Thromb Vasc Biol. 2003 May 1;23(5):795-801.
Zhan Y, Kim S, Kawano H, Iwao H. Enhancement of glomerular platelet-derived growth factor beta-receptor tyrosine phosphorylation in hypertensive rats and its inhibition by calcium channel blocker. Hypertens Res. 2002 Mar;25(2):295-301.
Zhan Y, Kim S, Yasumoto H, Namba M, Miyazaki H, Iwao H. Effects of dominant-negative c-Jun on platelet-derived growth factor-induced vascular smooth muscle cell proliferation. Arterioscler Thromb Vasc Biol. 2002 Jan;22(1):82-8.
Kim S, Zhan Y, Izumi Y, Yasumoto H, Yano M, Iwao H. In vivo activation of rat aortic platelet-derived growth factor and epidermal growth factor receptors by angiotensin II and hypertension. Arterioscler Thromb Vasc Biol. 2000 Dec;20(12):2539-45.
Kim S, Zhan Y, Izumi Y, Iwao H. Cardiovascular effects of combination of perindopril, candesartan, and amlodipine in hypertensive rats. Hypertension. 2000 Mar;35(3):769-74.
Posted on: Monday, August 24, 2009 - 03:28 PM; by: ming